Jaringan Laboratorium Medis

Vol. 4 No. 1 (2022): May 2022
Original Articles

Risk Analysis of AST and ALT level in Patients with Diabetes Mellitus Type 2

PDF
  • Mochamad Rizal Maulana,
  • Sutji Kuswarini
Mochamad Rizal Maulana
Poltekkes Kemenkes Semarang
Sutji Kuswarini
Universitas Airlangga

Published 2023-12-06

Keywords

  • Diabetes Mellitus,
  • Liver,
  • AST,
  • ALT

Copyright (c) 2022 Jaringan Laboratorium Medis

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

How to Cite

Risk Analysis of AST and ALT level in Patients with Diabetes Mellitus Type 2. (2023). Jaringan Laboratorium Medis, 4(1), 51-55. https://doi.org/10.31983/jlm.v4i1.8489

CrossMark



Dimensions

If it doesn't Appear, click here



PlumX Metrics



Impact Factor

or, Visit on here

Abstract

Diabetes mellitus is a group of metabolic diseases that occur due to abnormalities in insulin secretion and/or insulin action. In type 2 diabetes mellitus there is a decrease in glucose absorption by the body due to insulin resistance. Energy metabolism from glucose is processed through the synthesis of fatty acids in the liver (cytosol). The process that occurs continuously causes the accumulation of lipids in the liver or "fatty liver" so it is necessary to check the levels of transaminase enzymes which include SGOT and SGPT. The purpose of this study was to analyze the levels of SGOT and SGPT enzymes in patients with type 2 diabetes mellitus using the analytical observational method. The results of the examination of SGOT and SGPT levels from 30 patients who were taken randomly at Dr. Soetomo Surabaya will be analyzed with bar graphs and diagrams. Of 30 random samples, 20 samples (66.67%) had SGOT levels above the normal value, and 12 samples (40%) had SGPT with results above normal values. This study concludes that there is an increase in the levels of SGOT and SGPT enzymes in patients with type 2 diabetes mellitus.

PDF

Downloads

Download data is not yet available.

References

  1. American Diabetes Association. (2004). Diagnosis and Classification of Diabetes Mellitus. Diabetes care 27(S1)
  2. Corwin, E.J. (2009). Buku saku Patifisologi. Edisi 3. Alih Bahasa : Budhi. Penerbit Buku Kedokteran EGC. Jakarta
  3. Ditjen Bina Farmasi dan Alkes. (2005). Pharmaceutical Care untuk penyakit Diabetes Mellitus. Departemen Kesehatan RI. Jakarta
  4. Guyton dan Hall. (2007). Buku Ajar Fisiologi Kedokteran. Edisi II. Penerbit Buku Kedokteran EGC. Jakarta.
  5. Husadha, Y. (1996). Ilmu Penyakit Dalam “Fisiologi dan Pemeriksaan Biokimia”. Jilid I. Balai Penerbita UNHAS. Jakarta
  6. Kimbal, J.W. (2010). Biologi Umum. Penerbit Buku Erlangga. Jakarta
  7. Murray, Granner, Rodwell. (2009). Biokimia Harper. Edisi 27. Penerbit Buku Kedokteran EGC. Jakarta.
  8. Nilla Apriani Naim. Pemeriksaan SGOT dan SGPT: https://nillaaprianinaim.wordpress.com/2011/09/28/pemeriksaan-sgpt-dansgot, 24 November 2014, pukul 19.32
  9. Price A S, Wilson M N. (2005). Patofisiologi Konsep Klinis Proses – Proses Penyakit. Edisi 6. Alih Bahasa : Huriawati Hartanto. Penerbit Buku Kedokteran EGC. Jakarta.
  10. Price A S, Wilson M N. (2007). Patofisiologi Konsep Klinis Proses – Proses Penyakit. Edisi 7. Alih Bahasa : Huriawati Hartanto. Penerbit Buku Kedokteran EGC. Jakarta.
  11. Reny Yulita. Patofisiologi Diabetes Mellitus: http://renyyulita.blogspot.com/2012/01/patofisiologi-diabetes-melitus.html, 17 November 2014, pukul 18.37
  12. Santoso, Heri. (2013). Pengaruh Diabetes terhadap Kesehatan :http://hidupsehatnatura.blogspot.com/2013/03/pengaruh-diabetesterhadap-kesehatan.html, 17 November 2014, pukul 11.03
  13. Sridianti. Struktur Anatomi Hati: http://www.sridianti.com/struktur-anatomihati.html, 24 November 2014 13.10
  14. Trisnowati, C. (2019). SGOT and SGPT Levels in Patients with Dengue Hemorrhagic Fever. Jaringan Laboratorium Medis, 1(2), 98-101.